Additional Information
Short Description: |
20S Proteasome inhibitor |
Research Area: |
Cancer, Cancer Growth Inhibitors, Proteasome Inhibitors |
Alternative Name(s): |
(αS)-α-[[2-(4-morpholinyl)acetyl]amino]benzenebutanoyl-L-leucyl-N-[(1S)-3-methyl-1-[[(2R)-2-methyl-2-oxiranyl]carbonyl]butyl]-L-phenylalaninamide, PR-17, Carfilzomib, Kyprolis, Carfilzomib (PR-171), PR-171, UNII-72X6E3J5AR |
Category: |
Small Molecules |
Product Type: |
Inhibitor |
CAS No.: |
868540-17-4 |
Molecular Formula: |
C40H57N5O7 |
Molecular Weight: |
719,9 |
Source: |
Synthetic |
Purity: |
>98% (TLC); NMR (Conforms) |
Solubility: |
Soluble in DMSO (80 mg/ml), or ethanol (25 mg/ml) |
Appearance: |
White powder |
Storage: |
-20ºC |
Shipping: |
Shipped Ambient |
SMILES: |
O=C([C@]1(C)OC1)[C@H](CC(C)C)NC([C@@H](NC([C@@H](NC([C@H](CCC2=CC=CC=C2)NC(CN3CCOCC3)=O)=O)CC(C)C)=O)CC4=CC=CC=C4)=O |
InChI: |
1S/C40H57N5O7/c1-27(2)22-32(36(47)40(5)26-52-40)42-39(50)34(24-30-14-10-7-11-15-30)44-38(49)33(23-28(3)4)43-37(48)31(17-16-29-12-8-6-9-13-29)41-35(46)25-45-18-20-51-21-19-45/h6-15,27-28,31-34H,16-26H2,1-5H3,(H,41,46)(H,42,50)(H,43,48)(H,44,49)/ |
InChIKey: |
BLMPQMFVWMYDKT-NZTKNTHTSA-N |
Field of Use: |
For in vitro research use only. |
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