Description
Carglumic acid is an activator of carbamoyl phosphate synthetase 1 (CPS1), the first enzyme in the urea cycle that is responsible for removal and detoxification of ammonia, making this drug a valuable agent for therapy of hyperammonemia caused by rare forms of urea cycle defects.
Carglumic acid is an activator of carbamoyl phosphate synthetase 1 (CPS1), the first enzyme in the urea cycle that is responsible for removal and detoxification of ammonia, making this drug a valuable agent for therapy of hyperammonemia caused by rare forms of urea cycle defects.
B2447 | Carglumic acid DataSheet
Alternate Name/Synonyms: N-(aminocarbonyl)-L-glutamic acid, N-Carbamyl-L-Glutamic Acid
Appearance: White to off-white solid
Formulation:
CAS Number: 1188-38-1
Structure Available?:
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₆H₁₀N₂O₅
Molecular Weight: 190.15
Cell-Permeable?: True
Purity: ≥98%
Solubilities: ~30 mg/ml DMSO
Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.
Country of Origin: USA
Tag Line: An activator of carbamoyl phosphate synthetase 1 (CPS1)
MDL Number:
PubChem CID: 121396
SMILES: C(CC(=O)O)C(C(=O)O)NC(=O)N
InChi: InChI=1S/C6H10N2O5/c7-6(13)8-3(5(11)12)1-2-4(9)10/h3H,1-2H2,(H,9,10)(H,11,12)(H3,7,8,13)/t3-/m0/s1
InChi Key: LCQLHJZYVOQKHU-VKHMYHEASA-N
Additional Information
Storage Condition: |
-20ºC |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |