CARMA1 Antibody | 36-321

CARMA1 Antibody | 36-321 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: N-terminal human CARMA1 (aa 1-221 containing the CARD domain) .

Research Area: Cancer, Innate Immunity

Tested Application: ICC, IHC, WB

Application: Western Blot: (1ug/ml) .

Specificiy: Recognizes human and mouse CARMA1. Detects a band of ~130Dka by Western blot.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Polyclonal

Clone: N/A

Isotype: N/A

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Liquid. In PBS containing 10% glycerol and 0.02% sodium azide.

Concentration: 1 mg/ml

Storage Condition: Stable for at least 1 year after receipt when stored at -20˚C.

Alternate Name: CARD11; Bimp3; Caspase Recruitment Domain-containing Protein 11; CARD-containing MAGUK Protein 1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CARMA1 is involved in the costimulatory signal essential for T cell receptor (TCR) -mediated T cell activation. Its binding to DPP4 induces T cell proliferation and NF-kappaB activation in a T cell receptor/CD3-dependent manner. CARMA1 activates NF-kappaB via Bcl10 and IKK.