CASP3 | Caspase-3 (clone AM 1 4) | AS16 4001

CASP3 | Caspase-3 (clone AM 1 4) | AS16 4001 | Gentaur UK, US & Europe Distribution

Immunogen: Recombinant human Caspase-3 protein. UniProt: P42574

Host: Mouse

Conjugation: N/A

Clonality: Monoclonal

Isotype: IgG

Purity: Immunoglobulin IgG, Protein A/G purified.

Format: Liquid

Tested Application: Western blot (WB)

Related Products: anti-mouse secondary antibodies

Recommended Dilutions: The optimal working dilution should be determined by the investigator

Molecular weight: N/A

Confirmed Reactivity: Human

Predicted Reactivity: N/A

Not reactive in: No confirmed exceptions from predicted reactivity are currently known

Additional Information: N/A

Background: Caspase-3 is involved in the activation cascade of caspases, this cascade is responsible for apoptosis execution. It cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Caspase-3 belongs to the group of effector caspases that are involved in the cleavage of multiple substrates including the cytokeratins, PARP, alpha fodrin, NuMA and others.

Reconstitution: N/A

Storage: Store at 2 - 8 °C.

TAIR Nnumbre: N/A

Category: Neurobiology

Research Area: Neurobiology