Caspase-10 Antibody | 6677

Caspase family of cysteine proteases plays a key role in apoptosis. Caspase-10 is expressed in many tissues and cell lines. Similar to other caspases, caspase-10 is also synthesized as an inactive pro-enzyme that is processed in cells undergoing apoptosis. Four isoforms of caspase-10 have been identified: caspase-10a (Mch4), caspase-10b (FLICE2), caspase-10c and caspase-10d. They have the same prodomain but different mature large and small subdomains. Activated caspase-10 activates caspase-3,-4,-6,-7,-8, and –9, which are then involved in proteolytic cleavage of many cellular proteins. Caspase-10 has been shown to be involved in the Fas and TNFR1 - induced apoptosis.

6677 | Caspase-10 Antibody DataSheet

Antibody Target: Caspase-10

Target Alternative Name: FAS-associated death domain protein interleukin-1B-converting enzyme 2, FLICE2, ICE like Apoptotic Protease 4

Tag Line: Polyclonal Antibody to detect Caspase-10 in human samples

Category: Caspase-10

Host: Rabbit

Isotype: Rabbit IgG

Species Reactivities: Human

Immunogen Sequence: Human recombinant Caspase-10/a (Cat # 1090A)

Accession #: Q92851

Gene ID: 843

Appearance: Colorless liquid

Form: Liquid

Concentration: 0.5 mg/ml

Formulation: 100 µg (0.5 mg/ml) of Caspase-10 antibody in PBS pH 7.2, 0.01 % BSA, 0.01 % thimerosal, and 50 % glycerol.

Purification: Affinity Purified Antibody

Application: Western blot

Positive Control: Western Blot: Recombinant protein

Application And Usages: Western blot: 1-4 µg

Country of Animal Origin: USA

Country of Manufacture: USA

Usage: For Research Use Only! Not to be used in humans.

Handling: The antibody solution should be gently mixed before use.

Western Blot Verified: Verified

Immunocytochemistry Verified: Not Verified

Immunofluorescence Verified: Not Verified

Immunoprecipitation Verified: Not Verified

FACS Verified:

ELISA Verified: Not Verified

ChIP Verified: Not Verified

Dot Blot Verified: Not Verified

Flow Cytometry Verified: Not Verified