26
Caspase-13 Substrate LEED-AFC | 1116
- SKU:
- 26-1116-GEN
- Availability:
- Usually shipped in 5 working days
Description
Ready-to-use fluorometric substrate for caspase-13 and related caspases that recognize the amino acid sequence LEED. Caspase-13 and related caspase activity can be quantified by fluorescent detection of free AFC after cleavage from the peptide substrate LEED-AFC at Ex. = 400 nm and Em. = 505 nm, using a fluorometer or multi-well fluorescence plate reader. Alternatively, a shift in fluorescence from blue to green upon cleavage can be visualized using a hand-held long-UV lamp.
LEED-AFC is a ready-to-use fluorometric substrate for caspase-13 and related caspases that recognize the amino acid sequence LEED.
1116 | Caspase-13 Substrate LEED-AFC DataSheet
Alternate Name/Synonyms: Ac-LEED-AFC, Caspase-13 Substrate, Fluorogenic
Appearance: Liquid
Formulation: DMSO (4 mM)
CAS Number: N/A
Structure Available?: No
Peptide sequence: Ac-Leu-Glu-Glu-Asp-AFC
Salt Form: No
Molecular Formula: C₃₂H₃₈F₃N₅O₁₃
Molecular Weight: 757.66
Cell-Permeable?: No
Purity: >98% by HPLC
Solubilities: N/A
Handling: Protect from light and moisture
Country of Origin: USA
Tag Line: A caspase-13 substrate
MDL Number: MFCD03452816
PubChem CID: 44135106
SMILES: CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(CCC(=O)O)C(=O)NC(CC(=O)O)C(=O)NC1=CC2=C(C=C1)C(=CC(=O)O2)C(F)(F)F)NC(=O)C
InChi: InChI=1S/C32H38F3N5O13/c1-14(2)10-21(36-15(3)41)31(52)39-19(6-8-24(42)43)28(49)38-20(7-9-25(44)45)29(50)40-22(13-26(46)47)30(51)37-16-4-5-17-18(32(33,34)35)12-27(48)53-23(17)11-16/h4-5,11-12,14,19-22H,6-10,13H2,1-3H3,(H,36,41)(H,37,51)(H,38,49)(H,39,52)(H,40,50)(H,42,43)(H,44,45)(H,46,47)
InChi Key: ZPNCQMJLTSFJQH-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
12 months |