BW
Caspase-3 polyclonal Antibody | BS90186
- SKU:
- BW-BS90186
- Availability:
- Usually ships in 5 working days
Description
Caspase-3 polyclonal Antibody | BS90186 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse
Application: WB ICC IHC FC
Application Range: WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100
Background: Involved in the activation cascade of caspases responsible for apoptosis execution. At the onset of apoptosis it proteolytically cleaves poly (ADP-ribose) polymerase (PARP) at a '216-Asp-|-Gly-217' bond. Cleaves and activates sterol regulatory element binding proteins (SREBPs) between the basic helix-loop-helix leucine zipper domain and the membrane attachment domain. Cleaves and activates caspase-6, -7 and -9. Involved in the cleavage of huntingtin. Triggers cell adhesion in sympathetic neurons through RET cleavage.
Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.
Specificity: Caspase-3 polyclonal Antibody detects endogenous levels of Caspase-3 protein.
Molecular Weight: 32 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CASP-3, CPP-32, SCA-1, CASP3, CPP32, A830040C14Rik, Apopain, CASP-3, CASP3, CASP3, Casp3a, Caspase 3, Caspase 3, apoptosis-related cysteine peptidase, Caspase 3, apoptosis-related cysteine protease, Caspase 3, apoptosis-related cysteine protease a, Caspase-3 subunit p12, CC3, CPP-32, CPP32, CPP32B, Cysteine protease CPP32, EC 3.4.22.56, LICE, mldy, OTTHUMP00000165052, OTTHUMP00000165053, OTTHUMP00000165054, PARP cleavage protease, Procaspase3, Protein Yama, SCA 1, SCA-1, SREBP cleavage activity 1, Yama,
Immunogen: Peptide
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: Peptide affinity purified
Pathway: