Caspase-5 Inhibitor Z-WEHD-FMK | 1100

A synthetic peptide that irreversibly inhibits caspase-5 and related caspase activity. The inhibitor is designed as a methyl ester to facilitate cell permeability. (CAUTION: If the intended use is on purified or recombinant enzymes, esterase should be added to generate free carboxyl groups).

Z-ATAD-FMK is a cell-permeable, irreversible caspase-5 inhibitor.

1100 | Caspase-5 Inhibitor Z-WEHD-FMK DataSheet

Alternate Name/Synonyms: Z-WEHD-FMK, Caspase-5 Inhibitor (fluoromethylketone)

Appearance: Liquid

Formulation: DMSO (2 mM)

CAS Number: N/A

Structure Available?: No

Peptide sequence: Z-Trp-Glu(OMe)-His-Asp(OMe)-FMK

Salt Form: No

Molecular Formula: C₃₇H₄₂FN₇O₁₁

Molecular Weight: 763.78

Cell-Permeable?: yes

Purity: >99% by HPLC

Solubilities: N/A

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A caspase-5 inhibitor

MDL Number: MFCD03453283

PubChem CID: 44134610

SMILES: COC(=O)CCC(C(=O)NC(CC1=CN=CN1)C(=O)NC(CC(=O)OC)C(=O)CF)NC(=O)C(CC2=CNC3= CC=CC=C32)NC(=O)OCC4=CC=CC=C4

InChi: InChI=1S/C37H42FN7O10/c1-53-32(47)13-12-27(34(49)44-30(15-24-19-39-21- 41-24)36(51)43-28(31(46)17-38)16-33(48)54-2)42-35(50)29(14-23-18-40-26- 11-7-6-10-25(23)26)45-37(52)55-20-22-8-4-3-5-9-22/h3-11,18-19,21,27-30, 40H,12-17,20H2,1-2H3,(H,39,41)(H,42,50)(H,43,51)(H,44,49)(H,45,52)

InChi Key: NLZNSSWGRVBWIX-UHFFFAOYSA-N