Caspase-9 Substrate LEHD-pNA | 1076

Ready-to-use colorimetric substrate for caspase-9/Mch6 and related caspases that recognize the amino acid sequence LEHD. Caspase-9 and related caspase activity can be quantified by spectrophotometric detection of free pNA (l= 400 nm) after cleavage from the peptide substrate LEHD-pNA, using a spectrophotometer or multi-well plate reader.

LEHD-pNA is a ready-to-use fluorometric substrate for caspase-9/Mch-6 and related caspases that recognize the amino acid sequence LEHD.

1076 | Caspase-9 Substrate LEHD-pNA DataSheet

Alternate Name/Synonyms: Ac-LEHD-pNA, Caspase-9 Substrate, colorimetric, LEHD-pNA, LEHDPNA

Appearance: Liquid

Formulation: DMSO (4 mM)

CAS Number: N/A

Structure Available?: No

Peptide sequence: Ac-Leu-Glu-His-Asp-pNA

Salt Form: No

Molecular Formula: C₂₉H₃₈N₈O₁₁

Molecular Weight: 674.7

Cell-Permeable?: No

Purity: >98% by HPLC

Solubilities: N/A

Handling: Protect from light and moisture

Country of Origin: USA

Tag Line: A caspase-9 substrate

MDL Number: N/A

PubChem CID: 44135313

SMILES: CC(C)CC(C(=O)NC(CCC(=O)O)C(=O)NC(CC1=CN=CN1)C(=O)NC(CC(=O)O)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-])NC(=O)C

InChi: InChI=1S/C29H38N8O11/c1-15(2)10-21(32-16(3)38)28(45)34-20(8-9-24(39)40)26(43)35-22(11-18-13-30-14-31-18)29(46)36-23(12-25(41)42)27(44)33-17-4-6-19(7-5-17)37(47)48/h4-7,13-15,20-23H,8-12H2,1-3H3,(H,30,31)(H,32,38)(H,33,44)(H,34,45)(H,35,43)(H,36,46)(H,39,40)(H,41,42)

InChi Key: SHOGFKLEAOHMOJ-UHFFFAOYSA-N