LBD
CAV3 Antibody (N-term) [APR05759G]
- SKU:
- LBD-APR05759G
- Availability:
- Usually ships in 5 working days
Description
CAV3 Antibody (N-term) [APR05759G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This CAV3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 5-31 amino acids from the N-terminal region of human CAV3.
Cellular Localisation: Golgi apparatus membrane; Peripheral membrane protein. Cell membrane {ECO:0000250|UniProtKB:P51638}; Peripheral membrane protein. Membrane, caveola {ECO:0000250|UniProtKB:P51637}; Peripheral membrane protein. Cell membrane, sarcolemma {ECO:0000250|UniProtKB:P51637}. Note=Potential hairpin-like structure in the membrane. Membrane protein of caveolae (By similarity)
Molecular Weight: 17259
Clone: Polyclonal
Gene Name: CAV3
Gene ID: 859
Function: May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. May also regulate voltage-gated potassium channels. Plays a role in the sarcolemma repair mechanism of both skeletal muscle and cardiomyocytes that permits rapid resealing of membranes disrupted by mechanical stress (By similarity) . Mediates the recruitment of CAVIN2 and CAVIN3 proteins to the caveolae (PubMed:19262564) .
Summary: Tissue Location: Expressed predominantly in muscle.
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, FC
Dilution: WB--1:500 WB--1:1000 IHC-P--1:100~500 FC--1:10~50
Synonyms: Caveolin-3, M-caveolin, CAV3