CBX3 Polyclonal Antibody | E-AB-12511

CBX3 Polyclonal Antibody | E-AB-12511 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: CBX 3, CBX3, CBX3, Chromobox homolog 3 (HP1 gamma homolog, Drosophila), Chromobox homolog 3, Chromobox protein homolog 3, GAMMA, HECH, Heterochromatin like protein 1, Heterochromatin protein 1 homolog gamma, Heterochromatin protein HP1 gamma, HP1 gamma, HP1 gamma homolog, HP1Hs gamma, Modifier 2 protein

Application: WB, IHC, ELISA

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Epigenetics and Nuclear Signaling

Background: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks.

Concentration: 0.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human CBX3

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:500-1:2000, IHC 1:50-1:200

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 21 kDa

Molecular Weight(Observed): N/A