Description
CC-122 is a novel agent for DLBCL with antitumor and immunomodulatory activity.CC-122 binds CRBN and degrades Aiolos and Ikaros resulting in a mimicry of IFN signaling and apoptosis in DLBCL.
CC-122 is a novel agent for DLBCL with antitumor and immunomodulatory activity.CC-122 binds CRBN and degrades Aiolos and Ikaros resulting in a mimicry of IFN signaling and apoptosis in DLBCL.
Alternate Name/Synonyms: CC-122; CC122; CC 122; Avadomide; 3-(5-amino-2-methyl-4-oxoquinazolin-3(4H)-yl)piperidine-2,6-dione; 2,6-Piperidinedione, 3-(5-amino-2-methyl-4-oxo-3(4H)-quinazolinyl)-
Appearance: Solid
Formulation: N/A
CAS Number: 1015474-32-4
Structure Available?: Yes
Peptide sequence: N/A
Salt Form: No
Molecular Formula: C₁₄H₁₄N₄O₃
Molecular Weight: 286.29
Cell-Permeable?: Yes
Purity: >98%
Solubilities: DMSO
Handling: Protect from air and light
Country of Origin: USA
Tag Line: A novel agent for DLBCL
MDL Number: NA
PubChem CID: 24967599
SMILES: CC1=NC2=C(C(=CC=C2)N)C(=O)N1C3CCC(=O)NC3=O
InChi: InChI=1S/C14H14N4O3/c1-7-16-9-4-2-3-8(15)12(9)14(21)18(7)10-5-6-11(19)17-13(10)20/h2-4,10H,5-6,15H2,1H3,(H,17,19,20)
InChi Key: RSNPAKAFCAAMBH-UHFFFAOYSA-N
Additional Information
Storage Condition: |
-20°C |
Shipping Condition: |
Gel Pack |
Shelf Life: |
36 months |