CCBL1 Antibody | 22-298

CCBL1 Antibody | 22-298 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-270 of human CCBL1 (NP_001116144.1) .

Research Area: Cancer, Signal Transduction

Tested Application: WB, IHC, IF

Application: WB: 1:500 - 1:2000
IHC: 1:50 - 1:200
IF: 1:10 - 1:100

Specificiy: N/A

Positive Control 1: Raji

Positive Control 2: HeLa

Positive Control 3: SW620

Positive Control 4: Mouse liver

Positive Control 5: Mouse kidney

Positive Control 6: Mouse heart

Molecular Weight: Observed: 48kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CCBL1, cysteine conjugate-beta lyase, glutamine transaminase K, kyneurenine aminotransferase, GTK, KATI, MGC29624, cytoplasmic cysteine conjugate-beta lyase, glutamine-phenylpyruvate aminotransferase, kynurenine aminotransferase I, KAT1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a cytosolic enzyme that is responsible for the metabolism of cysteine conjugates of certain halogenated alkenes and alkanes. This metabolism can form reactive metabolites leading to nephrotoxicity and neurotoxicity. Increased levels of this enzyme have been linked to schizophrenia. Multiple transcript variants that encode different isoforms have been identified for this gene.