LBD
CCDC36 Antibody (C-term) [APR03612G]
- SKU:
- LBD-APR03612G
- Availability:
- Usually ships in 5 working days
Description
CCDC36 Antibody (C-term) [APR03612G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This CCDC36 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 422-450 amino acids from the C-terminal region of human CCDC36.
Cellular Localisation: Chromosome {ECO:0000250|UniProtKB:Q6PDM4}. Note=Specifically localizes to unsynapsed chromosomal regions during meiosis. {ECO:0000250|UniProtKB:Q6PDM4}
Molecular Weight: 66343
Clone: Polyclonal
Gene Name: IHO1 {ECO:0000303|PubMed:27723721, ECO:0000312|HGNC:HGNC:27945}
Gene ID: 339834
Function: Required for DNA double-strand breaks (DSBs) formation in unsynapsed regions during meiotic recombination. Probably acts by forming a complex with MEI4 and REC114, which activates DSBs formation in unsynapsed regions, an essential step to ensure completion of synapsis. Not required for HORMAD1 functions in pairing-independent synaptonemal complex formation, ATR recruitment to unsynapsed axes, meiotic silencing of unsynapsed chromatin (MSUC) or meiotic surveillance.
Summary: N/A
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: IHC-P, IF, WB
Dilution: WB--1:1000 IHC-P--1:100~500 IF--1:10~50
Synonyms: Coiled-coil domain-containing protein 36, Cancer/testis antigen 74, CT74, CCDC36