CCL14/HCC-1/HCC-3, human recombinant | 4275

Chemokine (C-C motif) ligand 14 (CCL14) is a small cytokine belonging to the CC chemokine family. It is also commonly known as HCC-1. It is produced as a protein precursor that is processed to generate a mature active protein containing 74 amino acids that and is 46% identical in amino acid composition to CCL3 and CCL4. This chemokine is expressed in various tissues including spleen, bone marrow, liver, muscle, and gut. CCL14 activates monocytes, but does not induce their chemotaxis. Human CCL14 is located on chromosome 17 within a cluster of other chemokines belonging to the CC family.

4275 | CCL14/HCC-1/HCC-3 human recombinant DataSheet

Biomolecule/Target: CCL-14

Synonyms: Chemokine CC-1/CC-3, HCC-1/HCC-3, HCC-1(1-74), NCC-2, Small-inducible cytokine A14

Alternates names: PK1, PRK1, Prokineticin 1, EG-VEGF, Endocrine-gland-derived vascular endothelial growth factor, Mambakine

Taglines: Activator of monocytes

NCBI Gene ID #: 84432

NCBI Gene Symbol: PROK1

Gene Source: Human

Accession #: P58294

Recombinant: Yes

Source: Mammalian cell expression system

Purity by SDS-PAGEs: 98%

Assay: SDS-PAGE

Purity: 95%

Assay #2: HPLC

Endotoxin Level: <0.1 ng/g (1 IEU/g)

Activity (Specifications/test method): N/A

Biological activity: Test in process

Results: N/A

Binding Capacity: N/A

Unit Definition: N/A

Molecular Weight: 9.5 kDa

Concentration: N/A

Appearance: Lyophilized protein

Physical form description: Lyophilized from a 0.2 m filtered solution of 20 mM PB and 150 mM NaCl, pH 7.2.

Reconstitution Instructions: Reconstitute in sterile PBS to a concentration of 0.1-1.0 mg/ml containing 0.1% BSA. This solution can then be diluted into other aqueous buffers

Amino acid sequence: N/A