LBD
CCL2 Antibody (C-term) [APR10832G]
- SKU:
- LBD-APR10832G
- Availability:
- Usually ships in 5 working days
Description
CCL2 Antibody (C-term) [APR10832G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H
Specificity: This CCL2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 62-89 amino acids from the C-terminal region of human CCL2.
Cellular Localisation: Secreted
Molecular Weight: 11025
Clone: Polyclonal
Gene Name: CCL2
Gene ID: 6347
Function: Acts as a ligand for C-C chemokine receptor CCR2 (PubMed:9837883, PubMed:10587439, PubMed:10529171) . Signals through binding and activation of CCR2 and induces a strong chemotactic response and mobilization of intracellular calcium ions (PubMed:9837883, PubMed:10587439) . Exhibits a chemotactic activity for monocytes and basophils but not neutrophils or eosinophils (PubMed:8627182, PubMed:9792674, PubMed:8195247) . May be involved in the recruitment of monocytes into the arterial wall during the disease process of atherosclerosis (PubMed:8107690) .
Summary: Tissue Location: Expressed in the seminal plasma, endometrial fluid and follicular fluid (at protein level) (PubMed:23765988) . Expressed in monocytes (PubMed:2513477) .
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: WB, IHC-P, IF, FC
Dilution: WB--1:1000 IHC-P--1:100~500 IF--1:10~50 FC--1:10~50
Synonyms: C-C motif chemokine 2, HC11, Monocyte chemoattractant protein 1, Monocyte chemotactic and activating factor, MCAF, Monocyte chemotactic protein 1, MCP-1, Monocyte secretory protein JE, Small-inducible cytokine A2, CCL2, MCP1, SCYA2