LBD
CCNY Antibody (Center) [APR30553G]
- SKU:
- LBD-APR30553G
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- Usually ships in 5 working days
Description
CCNY Antibody (Center) [APR30553G] | Gentaur UK, US & Europe Distribution
Product Category: Polyclonal Antibodies
Host: Rabbit
Species Reactivity: H, M
Specificity: This CCNY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 140-169 amino acids from the Central region of human CCNY.
Cellular Localisation: Cell membrane; Lipid-anchor; Cytoplasmic side
Molecular Weight: 39337
Clone: Polyclonal
Gene Name: CCNY
Gene ID: 219771
Function: Positive regulatory subunit of the cyclin-dependent kinases CDK14/PFTK1 and CDK16. Acts as a cell-cycle regulator of Wnt signaling pathway during G2/M phase by recruiting CDK14/PFTK1 to the plasma membrane and promoting phosphorylation of LRP6, leading to the activation of the Wnt signaling pathway. Recruits CDK16 to the plasma membrane. Isoform 3 might play a role in the activation of MYC-mediated transcription.
Summary: Tissue Location: Widely expressed..
Form: Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
Storage: Maintain refrigerated at 2-8°C for up to 2 weeks. For long term storage store at -20°C in small aliquots to prevent freeze-thaw cycles.
Application: IHC-P, WB
Dilution: IHC-P--1:100 WB--1:1000
Synonyms: Cyclin-Y, Cyc-Y, Cyclin box protein 1, Cyclin fold protein 1, cyclin-X, CCNY, C10orf9, CBCP1, CFP1