CD11c Antibody [HC1/1] | 33-158

CD11c Antibody [HC1/1] | 33-158 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: Human monocytic U937 phorbol ester-treated cells were used as the immunogen for this CD11c antibody.

Research Area: Immunology, Signal Transduction

Tested Application: Flow, IF, Bl

Application: Flow Cytometry: 0.5-1 ug/million cells
IF: 0.5-1 ug/ml
Functional Activity (Blocking) : order BSA/azide free format

The concentration stated for each application is a general starting point. Variations in protocols, secondaries and substrates may require the CD11c antibody to be titered up or down for optimal performance.

Specificiy: N/A

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: Protein G affinity chromatography

Clonality: Monoclonal

Clone: HC1/1

Isotype: IgG1, kappa

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.1 mg/ml BSA and 0.05% sodium azide

Concentration: 0.2 mg/mL

Storage Condition: Aliquot and Store at 2-8˚C. Avoid freez-thaw cycles.

Alternate Name: Integrin alpha-X, CD11 antigen-like family member C, Leu M5, Leukocyte adhesion glycoprotein p150, 95 alpha chain, Leukocyte adhesion receptor p150, CD11c, ITGAX, CD11C

User Note: Optimal dilutions for each application to be determined by the researcher

BACKGROUND: CD11c, also known as Integrin alpha X (complement component 3 receptor 4 subunit) (ITGAX) , is a type I transmembrane protein found at high levels on most human dendritic cells, but also on monocytes, macrophages, neutrophils, and some B cells that induces cellular activation and helps trigger neutrophil respiratory burst; expressed in hairy cell leukemias, acute non-lymphocytic leukemias, and some B-cell chronic lymphocytic leukemias.