CD14 Antibody [61D3] (APC-Cy7) | 99-489

CD14 Antibody [61D3] (APC-Cy7) | 99-489 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Cynomolgus, Dog, Hooded Seal

Homology: N/A

Immunogen: Human peripheral monocytes

Research Area: Immunology, Signal Transduction

Tested Application: IHC-Fr, Flow, Blocking, Adhesion, Costimulation

Application: CD14 Antibody [61D3] for use in flow cytometry assays.

Specificiy: CD14

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [61D3]

Isotype: IgG1

Conjugate: APC-Cy7

Physical State: Liquid

Buffer: Supplied in PBS/NaN3 and a stabilizing agent

Concentration: Lot specific

Storage Condition: Store vial at 2-8˚C

Alternate Name: LPS-R, LPS receptor, gp55

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD14 is a 55 kDa glycosphosphatidylinositol (GPI) -anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells, and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.