CD14 Antibody [UCHM-1] | 99-474

CD14 Antibody [UCHM-1] | 99-474 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Cynomolgus

Homology: N/A

Immunogen: Thymocytes and peripheral blood lymphocytes from a remission AML patient

Research Area: Immunology, Signal Transduction

Tested Application: Flow

Application: CD14 Antibody [UCHM-1] for use in flow cytometry, immunohistochemistry / immunocytochemistry, immunoprecipitation, ELISA, depletion, and blocking assays.

Specificiy: CD14

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [UCHM-1]

Isotype: IgG2a

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Concentration: 0.1 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: LPS-R, LPS receptor, gp55

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD14 is a 55 kDa glycosphosphatidylinositol (GPI) -anchored single chain glycoprotein. It is expressed on monocytes, macrophages, dendritic cells, and Langerhans cells. It is also weakly expressed on neutrophils. CD14 appears to be involved in clearance of gram-negative bacteria via its high affinity binding to LPS-LPB complexes.