BW
CD144 polyclonal Antibody | BS62255
- SKU:
- BW-BS62255
- Availability:
- Usually ships in 5 working days
Description
CD144 polyclonal Antibody | BS62255 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse
Application: WB IHC
Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200
Background: The cadherins are a family of Ca 2+-dependent adhesion molecules that function to mediate cell-cell binding critical to the maintenance of tissue structure and morphogenesis. Cadherins each contain a large extracellular domain at the amino-terminus, which is characterized by a series of five homologous repeats, the most distal of which is thought to be responsible for binding specificity. The relatively short carboxy-terminal, intracellular domain interacts with a variety of cytoplasmic proteins, including β-catenin, to regulate cadherin function. VE-cadherin (for vascular endothelial cadherin, also designated cadherin-5) is localized at intercellular junctions of endothelial cells, where it is thought to play a role in the cohesion and organization of intercellular junctions.
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CD144 polyclonal Antibody detects endogenous levels of CD144 protein.
Molecular Weight: ~ 98, 140 kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: CDH5; Cadherin-5; 7B4 antigen; VE-Cadherin; Vascular endothelial cadherin; CD144
Immunogen: Synthetic peptide, corresponding to Human CD144.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: Examples of Crosstalk Between Post-translational Modifications,DNA Methylation,