CD156c Polyclonal Antibody | E-AB-14498

CD156c Polyclonal Antibody | E-AB-14498 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: A disintegrin and metalloprotease domain 10, A disintegrin and metalloproteinase domain 10, AD 10, AD10, AD18, ADA10, ADAM 10, ADAM metallopeptidase domain 10, ADAM10, CD 156c, CD156c, CD156c antigen, CDw156, disintegrin and metalloproteinase domain containing protein 10, Disintegrin and metalloproteinase domain-containing protein 10, HsT 18717, HsT18717, Kuz, Kuzbanian, Kuzbanian protein homolog, Kuzbanian, Drosophila, homolog of, MADM, Mammalian disintegrin metalloprotease, Mammalian disintegrin-metalloprotease, RAK

Application: WB, IHC, ELISA

Reactivity: Human, Mouse, Rat

Host: Rabbit

Isotype: IgG

Reserch Areas: Cancer, Cell Biology, Signal Transduction

Background: Members of the ADAM family are cell surface proteins with a unique structure possessing both potential adhesion and protease domains. This gene encodes and ADAM family member that cleaves many proteins including TNF-alpha and E-cadherin. Cleaves the membrane-bound precursor of TNF-alpha at '76-Ala-|-Val-77' to its mature soluble form. Responsible for the proteolytical release of soluble JAM3 from endothelial cells surface. Responsible for the proteolytic release of several other cell-surface proteins, including heparin-binding epidermal growth-like factor, ephrin-A2 and for constitutive and regulated alpha-secretase cleavage of amyloid precursor protein (APP).

Concentration: 0.3 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant protein of human ADAM10

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:200-1:1000, IHC 1:25-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 84 kDa

Molecular Weight(Observed): N/A