CD159a/KLRC1 polyclonal Antibody | BS6275

CD159a/KLRC1 polyclonal Antibody | BS6275 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse

Application: WB

Application Range: WB 1:500 - 1:2000

Background: Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also regulate specific humoral and cell-mediated immunity. The protein encoded by this gene belongs to the killer cell lectin-like receptor family, also called NKG2 family, which is a group of transmembrane proteins preferentially expressed in NK cells. This family of proteins is characterized by the type II membrane orientation and the presence of a C-type lectin domain. This protein forms a complex with another family member, KLRD1/CD94, and has been implicated in the recognition of the MHC class I HLA-E molecules in NK cells.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: KLRC1 polyclonal Antibody detects endogenous levels of KLRC1 protein.

Molecular Weight: ~ 26 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CD159a; CD159a antigen; Killer cell lectin like receptor subfamily C member 1; KLRC1; MGC13374; MGC59791; Natural killer cell lectin; NKG2; NKG2 B; NKG2-A/B-activating NK receptor; NKG2-A/NKG2-B type II integral membrane protein; NKG2A; NKG2A; NKG2B; rNKG2A;

Immunogen: Recombinant full length Human CD159a/KLRC1.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: Necrotic Cell Death,Death Receptor Signaling,