CD180 polyclonal Antibody | BS61344

CD180 polyclonal Antibody | BS61344 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse

Application: WB

Application Range: WB: 1:500~1:1000 IHC: 1:50~1:200

Background: RP105 is a mouse B-cell surface molecule that transmits a growth-promoting signal and is implicated in the life/death decision of B cells. RP105 has tandem repeats of a leucine-rich motif in its extracellular domain that are presumed to be involved in protein-protein interactions. The amino acid sequence of human RP105 is highly homologous to that of mouse RP105; human RP105 shares 74% identity with the mouse protein, as well as the leucine-rich motif. Surface expression of RP105 is enhanced in the presence of MD1, although this expression is restricted to CD19-positive B cells. RP105 demonstrates predominant expression on mature B cells in mantle zones; very little expression is observed in germinal centers.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD180 polyclonal Antibody detects endogenous levels of CD180 protein.

Molecular Weight: ~ 74 kD

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CD180 antigen; Lymphocyte antigen 64; Radioprotective 105 kDa protein; CD_antigen: CD180; LY64, RP105

Immunogen: A synthetic peptide corresponding to residues in Human CD180 .

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 96% (by SDS-PAGE) .

Pathway: