CD1a Antibody| F43045-0.08ML/F43045-0.4ML/F53637-0.1ML/R30975/V2025-20UG/V2025IHC-7ML

CD1a Antibody| F43045-0.08ML/F43045-0.4ML/F53637-0.1ML/R30975/V2025-20UG/V2025IHC-7ML | Gentaur UK, US & Europe Distribution

Background: This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: N/A

Application: WB, IHC, ELISA

Application Details: Western blot: 1:1000, IHC (Paraffin): 1:10-1:50

Application Note: Titration of the CD1a antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This CD1a antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 75-104 from the human protein was used as the immunogen for this CD1a antibody.

Storage: Aliquot the CD1a antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A