CD207 Polyclonal Antibody | E-AB-40044

CD207 Polyclonal Antibody | E-AB-40044 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: C type lectin domain family 4 member K, C-type lectin domain family 4 member K, CD 207, CD207, CD207 antigen, CD207 antigen, langerin, CD207 molecule, CLC4K, CLEC 4K, CLEC4K, Langerhans cell specific c type lectin, Langerin, RGD1565913

Application: IHC

Reactivity: Human, Mouse

Host: Rabbit

Isotype: IgG

Reserch Areas: Metabolism, Signaling transduction

Background: Calcium-dependent lectin displaying mannose-binding specificity. Induces the formation of Birbeck granules (BGs); is a potent regulator of membrane superimposition and zippering. Binds to sulfated as well as mannosylated glycans, keratan sulfate (KS) and beta-glucans. Facilitates uptake of antigens and is involved in the routing and/or processing of antigen for presentation to T cells. Major receptor on primary Langerhans cells for Candida species, Saccharomyces species, and Malassezia furfur. Protects against human immunodeficiency virus-1 (HIV-1) infection. Binds to high-mannose structures present on the envelope glycoprotein which is followed by subsequent targeting of the virus to the Birbeck granules leading to its rapid degradation.

Concentration: 2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Recombinant human C-type lectin domain family 4 member K protein

Buffer: PBS with 0.02% sodium azide and 50% glycerol pH 7.4.

Purification Method: Affinity purification

Dilution: IHC 1:50-1:100

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): N/A

Molecular Weight(Observed): N/A