Description
CD23 Antibody [T��1] (PE) | 99-501 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Purified human tonsil lymphocytes
Research Area: Immunology, Stem Cell, Cancer, Cell Cycle
Tested Application: Flow
Application: CD23 Antibody [T��1] for use in flow cytometry assays.
Specificiy: CD23
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [T��1]
Isotype: IgG3
Conjugate: PE
Physical State: Liquid
Buffer: Supplied in PBS/NaN3 and a stabilizing agent
Concentration: Lot specific
Storage Condition: Store vial at 2-8˚C
Alternate Name: FCepsilonRII, B6, Leu-20, BLAST-2, low affinity IgE receptor
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD23 is a 45 kDa type II integral membrane glycoprotein that is the low affinity receptor for IgE. It also binds to CD21 and the alpha chains of CD11b and CD11c. It is expressed by B cells and monocytes and, weakly, on T cells, follicular dendritic cells, eosinophils, NK cells, Langerhans cells, and platelets. It is upregulated in response to B cell activation, CD40 ligation, or in response to IL-4 or IL-13. CD23 is responsible for regulation of IgE synthesis and may play a role in antigen presentation by B cells and follicular dendritic cells by interacting with CD40.