CD276 polyclonal Antibody | BS90229

CD276 polyclonal Antibody | BS90229 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human (predicted:Mouse)

Application: WB ICC IHC FC

Application Range: WB:1:500-1:2,000 ICC:1:50-1:200 IHC:1:50-1:200 FC:1:50-1:100

Background: May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C. Avoid repeated freeze / thaw cycles.

Specificity: CD276 polyclonal Antibody detects endogenous levels of CD276 protein.

Molecular Weight: 57 kDa (Predicted band size)

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: B7-H3, CD276, B7H3, PSEC0249, UNQ309/PRO352, 4Ig B7 H3, 4Ig-B7-H3, AU016588, B7 H3, B7 homolog 3, B7-H3, B7H3, B7RP-2, CD_antigen=CD276, CD276, CD276 antigen, CD276 molecule, CD276, Costimulatory molecule, Flags: Precursor, PSEC0249, UNQ309/PRO352,

Immunogen: Recombinant protein within human CD276 280-500 aa.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein affinity purified.

Pathway: Tumor-Infiltrating Immune Cell Marker Guide,