Gentaur

CD278 [ICOS] (human):Fc (human) (rec.) | CHI-HF-210ICOS-C025

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SKU:
CHI-HF-210ICOS-C025-GEN
Availability:
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£326.00

Description

CD278 [ICOS] (human):Fc (human) (rec.) | CHI-HF-210ICOS-C025

CD278, also called inducible costimulator (ICOS) or CRP1 (CD28-related protein-1), is a member of the growing CD28 family of immune costimulatory receptors. Other family members are CD28, CTLA-4 and PD-1. ICOS is expressed on most CD45RO+ cells. ICOS expression is upregulated within approximately 24-48 hours of activation on Th primed cells. B7-H2, a member of the B7 family of costimulatory ligands, has been identified as the ICOS ligand. The B7-H2/ICOS interaction appears to play roles in T cell dependent B cell activation and Th differentiation.

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Additional Information

Size:
25 µg
Source/Host:
CHO cells
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