CD28 Antibody [37.51] (PE-Cy5) | 98-718

CD28 Antibody [37.51] (PE-Cy5) | 98-718 | Gentaur UK, US & Europe Distribution

Host: Hamster

Reactivity: Mouse

Homology: N/A

Immunogen: C57BL/6N mouse T cell lymphoma EL-4 cell line

Research Area: Immunology

Tested Application: Flow

Application: CD28 Antibody [37.51] for use in flow cytometry assays.

Specificiy: CD28

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [37.51]

Isotype: IgG

Conjugate: PE-Cy5

Physical State: Liquid

Buffer: Supplied in PBS/NaN3 and a stabilizing agent

Concentration: 0.1 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: Tp44, T44

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD28 is a type I disulfide-linked homodimer that is constitutively expressed on most thymocytes, at low density on nearly all CD4+ and CD8+ peripheral T lymphocytes and at very low levels on NK cells. Its expression is upregulated upon T-cell activation. CD28 is a ligand for CD80 (B7-1) and CD86 (B7-2) on B cells and other antigen presenting cells and plays an important role in the interaction between T cells and B cells. CD28 is a costimulatory receptor involved in many, but not all, T-cell independent immune responses.