CD283 Antibody [TLR3.7] (PE) | 76-955

CD283 Antibody [TLR3.7] (PE) | 76-955 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: N/A

Research Area: Innate Immunity

Tested Application: Flow

Application: N/A

Specificiy: The TLR3.7 monoclonal antibody specifically reacts with human CD283 (TLR3) , a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain.

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: The monoclonal antibody was purified utilizing affinity chromatography and unreacted dye was removed from the product.

Clonality: Monoclonal

Clone: TLR3.7

Isotype: Mouse IgG1, kappa

Conjugate: PE

Physical State: liquid

Buffer: Phosphate-buffered aqueous solution, ≤0.09% Sodium azide, may contain carrier protein/stabilizer, ph7.2.

Concentration: batch dependent

Storage Condition: The product should be stored undiluted at 4˚C and should be protected from prolonged exposure to light. Do not freeze.

Alternate Name: CD283, IIAE2, TLR3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The TLR3.7 monoclonal antibody specifically reacts with human CD283 (TLR3) , a type I transmembrane signaling receptor containing IL-1 receptor like intracellular domain and leucine-rich repeats (LRR) in the extracellular domain. It is expressed by dendritic cells and recognize double-stranded RNA and polyinosine-polycytidylic acid. Upon ligand binding, CD283 induces type I interferon production and activation of the nuclear factor kappa-light-chain-enhancer of activated B cells complex (NF-κB) .