CD2AP Polyclonal Antibody | E-AB-16309

CD2AP Polyclonal Antibody | E-AB-16309 | Gentaur UK, US & Europe Distribution

Type: Polyclonal Antibody

Synonyms: Adapter protein CMS, AL024079, C78928, Cas ligand with multiple SH3 domains, CD2 associated protein, CD2-associated protein, CD2AP, CD2AP, CMS, Mesenchyme to epithelium transition protein with SH3 domains 1, METS 1, Mets1

Application: WB, IHC, ELISA

Reactivity: Human

Host: Rabbit

Isotype: IgG

Reserch Areas: Signal transduction

Background: This gene encodes a scaffolding molecule that regulates the actin cytoskeleton. The protein directly interacts with filamentous actin and a variety of cell membrane proteins through multiple actin binding sites, SH3 domains, and a proline-rich region containing binding sites for SH3 domains. The cytoplasmic protein localizes to membrane ruffles, lipid rafts, and the leading edges of cells. It is implicated in dynamic actin remodeling and membrane trafficking that occurs during receptor endocytosis and cytokinesis. Haploinsufficiency of this gene is implicated in susceptibility to glomerular disease.

Concentration: 0.2 mg/mL

Storage: Store at -20°C. Avoid freeze / thaw cycles.

Immunogen: Synthetic peptide of human CD2AP

Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4

Purification Method: Affinity purification

Dilution: WB 1:1000-1:5000, IHC 1:100-1:300

Clone: N/A

Conjugation: Unconjugated

Molecular Weight(Calculated): 71 kDa

Molecular Weight(Observed): N/A