CD3 Antibody [UCHT1] | 99-412

CD3 Antibody [UCHT1] | 99-412 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human

Homology: N/A

Immunogen: Human peripheral blood lymphocytes from a patient with S��zary's syndrome and infant thymocytes

Research Area: Cancer, Immunology, Signal Transduction

Tested Application: Flow

Application: CD3 Antibody [UCHT1] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, activation, and blocking assays.

Specificiy: CD3

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [UCHT1]

Isotype: IgG1

Conjugate: Unconjugated

Physical State: Liquid

Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added

Concentration: 0.1 mg/mL

Storage Condition: Store vial at 2-8˚C

Alternate Name: CD3epsilon, T3E, TCRE, Leu-4, T3

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD3, a member of the immunoglobulin superfamily of cell surface receptors, is comprised of five invariable chains ranging from 16-28 kDa and is closely associated with the T cell antigen receptor (TCR) . CD3 is expressed on 70-80% of normal peripheral blood lymphocytes and on 10-20% of thymocytes. It plays a major role in signaling during antigen recognition, leading to T cell activation. The monoclonal antibody UCHT1 reacts with the 20 kDa epsilon chain of the CD3/TCR complex.