CD34 polyclonal Antibody | BS90234

CD34 polyclonal Antibody | BS90234 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,mouse,rat

Application: WB ICC IHC FC

Application Range: WB:1:1,000-1:2,000 ICC:1:200 IHC:1:2,000-1:3,000 FC:1:50-1:100

Background: CD34 is a heavily glycosylated type I transmembrane molecule, that can be phoshorylated by a variety of kinases including Protein kinase C and Tyrosine kinases. CD34 antigen is expressed on small vessel endothelial cells and tumors of epithelial origin. CD34 is possibly an adhesion molecule with a putative role in early hematopoiesis by mediating the attachment of stem cells to the bone marrow extracellular matrix or directly to stromal cells. It could act as a scaffold for the attachment of lineage specific glycans, allowing stem cells to bind to lectins expressed by stromal cells or other marrow components. So CD34 is considered to be ideal marker for identifying and quantifying hematopoietic progenitor stem cells. With interaction with CrkL, CD34 becomes a substrate for PKC and CD34 surface expression is associated with activation of PKC.

Storage & Stability: Store at +4°C after thawing. Aliquot store at -20°C or -80°C. Avoid repeated freeze / thaw cycles.

Specificity: CD34 polyclonal Antibody detects endogenous levels of CD34 protein.

Molecular Weight: 120 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CD34, CD34, CD34 antigen, CD34 molecule, CD34, Cluster designation 34, Hematopoietic progenitor cell antigen CD34, HPCA1, Mucosialin, OTTHUMP00000034733, OTTHUMP00000034734,

Immunogen: peptide

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Peptide affinity purified

Pathway: