CD3e Antibody| F43038-0.08ML/F43038-0.4ML/R35652-100UG

CD3e Antibody| F43038-0.08ML/F43038-0.4ML/R35652-100UG | Gentaur UK, US & Europe Distribution

Background: The protein encoded by this gene is the CD3-epsilon polypeptide, which together with CD3-gamma, -delta and -zeta, and the T-cell receptor alpha/beta and gamma/delta heterodimers, forms the T-cell receptor-CD3 complex. This complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. The genes encoding the epsilon, gamma and delta polypeptides are located in the same cluster on chromosome 11. The epsilon polypeptide plays an essential role in T-cell development. Defects in this gene cause immunodeficiency. This gene has also been linked to a susceptibility to type I diabetes in women.

Format: Antigen affinity purified

Clone: N/A

Host Animal: Rabbit

Clonality: Polyclonal (rabbit origin)

Isotype: Rabbit Ig

Species Reactivity: Human

Predicted Spacies Reactivity: Primate

Application: WB, ELISA

Application Details: Western blot: 1:1000

Application Note: Titration of the CD3e antibody may be required due to differences in protocols and secondary/substrate sensitivity.

Status: Available

Buffer: N/A

Limitation: This CD3e antibody is available for research use only.

Purity: Antigen affinity

Immunogen: A portion of amino acids 154-182 from the human protein was used as the immunogen for this CD3e antibody.

Storage: Aliquot the CD3e antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

Localization: N/A