Description
CD56 Antibody [MEM 188] | 99-393 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human, Pig
Homology: N/A
Immunogen: Acute myelogenous leukemia cell line KG-1
Research Area: Innate Immunity
Tested Application: IHC-P, IHC-Fr, Flow
Application: CD56 Antibody [MEM 188] for use in flow cytometry, immunohistochemistry / immunocytochemistry, separation, and blocking assays.
Specificiy: CD56
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [MEM 188]
Isotype: IgG2a
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration: 0.1 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: NCAM, neural cell adhesion molecule, Leu-19, NKH1
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD56, an isoform of the neural cell adhesion molecule (NCAM) , is a heavily glycosylated type I transmembrane protein. On human hematopoietic cells its expression is restricted to NK cells and a subpopulation of T lymphocytes (known as large granular lymphocytes) which demonstrate natural killer activity. While it is clear that NCAM plays a role in homotypic adhesion of neuronal cells, the significance of CD56 expression on NK cells is not clear and remains controversial.