CD56 Antibody [MEM 188] (Biotin) | 99-395

CD56 Antibody [MEM 188] (Biotin) | 99-395 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Pig

Homology: N/A

Immunogen: Acute myelogenous leukemia cell line KG-1

Research Area: Innate Immunity

Tested Application: E, Flow, Blocking, IP, Costimulation

Application: CD56 Antibody [MEM 188] for use in flow cytometry, immunohistochemistry / immunocytochemistry, and separation assays.

Specificiy: CD56

Positive Control 1: N/A

Positive Control 2: N/A

Positive Control 3: N/A

Positive Control 4: N/A

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: N/A

Validation: N/A

Isoform: N/A

Purification: N/A

Clonality: Monoclonal

Clone: [MEM 188]

Isotype: IgG2a

Conjugate: Biotin

Physical State: Liquid

Buffer: Supplied in PBS/NaN3

Concentration: Lot specific

Storage Condition: Store vial at 2-8˚C

Alternate Name: NCAM, neural cell adhesion molecule, Leu-19, NKH1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: CD56, an isoform of the neural cell adhesion molecule (NCAM) , is a heavily glycosylated type I transmembrane protein. On human hematopoietic cells its expression is restricted to NK cells and a subpopulation of T lymphocytes (known as large granular lymphocytes) which demonstrate natural killer activity. While it is clear that NCAM plays a role in homotypic adhesion of neuronal cells, the significance of CD56 expression on NK cells is not clear and remains controversial.