CD58 polyclonal Antibody | BS5657

CD58 polyclonal Antibody | BS5657 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human,Mouse,Rat

Application: WB

Application Range: WB: 1:500~1:1000

Background: CD2 (also designated E-rosette receptor) interacts through its amino-terminal domain with the extracellular domain of CD58 (also designated CD2 ligand) to mediate cell adhesion. CD2/CD58 binding can enhance antigen-specific T cell activation. CD2 is a transmembrane glycoprotein that is expressed on T lymphocytes, NK cells and thymocytes, as well as on mouse B cells and rat splenic macrophages. CD58 is a heavily glycosylated protein with a broad tissue distribution in hematopoietic and other cells, including endothelium.

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD58 polyclonal Antibody detects endogenous levels of CD58 protein.

Molecular Weight: ~ 65-70 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: Lymphocyte function-associated antigen 3; Ag3; Surface glycoprotein LFA-3; LFA3

Immunogen: Synthetic peptide, corresponding to amino acids 78-123 of Human CD58.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .

Pathway: