Description
CD74 Antibody [LN2] | 99-589 | Gentaur UK, US & Europe Distribution
Host: Mouse
Reactivity: Human
Homology: N/A
Immunogen: Cell line SU-DHL-4 nuclei
Research Area: Other
Tested Application: Flow
Application: CD74 Antibody [LN2] for use in flow cytometry, immunohistochemistry / immunocytochemistry, western blotting, immunoprecipitation, and blocking assays.
Specificiy: CD74
Positive Control 1: N/A
Positive Control 2: N/A
Positive Control 3: N/A
Positive Control 4: N/A
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: N/A
Validation: N/A
Isoform: N/A
Purification: N/A
Clonality: Monoclonal
Clone: [LN2]
Isotype: IgG1
Conjugate: Unconjugated
Physical State: Liquid
Buffer: Supplied in borate buffered saline, pH 8.2; No preservatives or amine-containing buffer salts added
Concentration: 0.1 mg/mL
Storage Condition: Store vial at 2-8˚C
Alternate Name: Invariant chain, Ii, class II-specific chaperone
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: CD74 represents a type II integral membrane protein known as MHC class II-associated invariant chain. It is moderately expressed on B cells and weakly on monocytes and macrophages. CD74 is also found on a subset of activated T cells, Langerhans cells, dendritic cells, and some epithelial cells. CD74 may play a role in antigen processing and presentation through intracellular transport and expression of class II molecules on the cell surface.