CD79a polyclonal Antibody | BS90259

CD79a polyclonal Antibody | BS90259 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human

Application: WB IF IHC FC

Application Range: WB:1:500-1:1,000 IHC:1:50-1:200 IF:1:50-1:100 FC:1:50-1:100

Background: The mb-1 gene codes for a phosphoprotein, designated CD79a, that, together with the related CD79b protein, forms a dimer associated with membrane-bound immunoglobulin in B-cells. The CD79a/CD79b dimer is closely associated with the B-cell antigen receptor, in a similar manner to the association of CD3 with the T-cell receptor, and enables the cell to respond to the presence of antigens on its surface. The CD79a protein is present on the surface of B-cells throughout their life cycle, and is absent on all other healthy cells, making it a highly reliable marker for B-cells in immunohistochemistry. The B lymphocyte antigen receptor is a multimeric complex that includes the antigen-specific component, surface immunoglobulin (Ig) . Surface Ig non-covalently associates with two other proteins, Ig-alpha and Ig-beta, which are necessary for expression and function of the B-cell antigen receptor. This gene encodes the Ig-alpha protein of the B-cell antigen component. Alternatively spliced transcript variants encoding different isoforms have been described.

Storage & Stability: Store at +4℃ after thawing. Aliquot store at -20℃. Avoid repeated freeze / thaw cycles.

Specificity: CD79a polyclonal Antibody detects endogenous levels of CD79a protein.

Molecular Weight: 38 kDa, predicted molecular weight 25 kDa.

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CD79a, CD79A, IGA, MB1, B lymphocyte-specific MB1 protein, B-cell antigen receptor complex-associated protein alpha chain, CD 79a, CD79a, CD79a antigen (immunoglobulin-associated alpha), CD79A antigen, CD79a molecule, immunoglobulin-associated alpha, CD79A, Ig alpha, Ig-alpha, IGA, IgM-alpha, Immunoglobulin-associated alpha, Ly54, MB-1 membrane glycoprotein, MB1, Membrane-bound immunoglobulin-associated protein, Surface IgM-associated protein Antibody

Immunogen: Recombinant protein within human CD79a aa 33-143.

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: Protein A purified.

Pathway: Immune checkpoint signaling in the Tumor Microenvironment,