CD8 polyclonal Antibody | BS65582

CD8 polyclonal Antibody | BS65582 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Mouse,

Application: WB,

Application Range: WB=1:500-2000 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user.

Background: The CD8 antigen is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. The CD8 antigen acts as a coreceptor with the T-cell receptor on the T lymphocyte to recognize antigens displayed by an antigen presenting cell in the context of class I MHC molecules. The coreceptor functions as either a homodimer composed of two alpha chains or as a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. This gene encodes the CD8 alpha chain. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].

Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: CD8 polyclonal Antibody detects endogenous levels of CD8 protein.

Molecular Weight: ~32kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Names: CD8 antigen, alpha polypeptide (p32) ; CD8a; CD8a antigen; CD8a molecule; CD8A_MOUSE; Leu2; Leu2 T lymphocyte antigen; MAL; OKT8 T cell antigen; p32; T cell antigen Leu2; T cell co receptor; T-cell surface glycoprotein CD8 alpha chain; T-lymphocyte differentiation antigen T8/Leu-2; T8 T cell antigen.

Immunogen: KLH conjugated synthetic peptide derived from mouse CD8:51-150/247

Conjugate: Unconjugated

Modification: Unmodification

Purification & Purity: affinity purified by Protein A

Pathway: