Description
CD83 is a single-pass type I membrane protein and member of the immunoglobulin superfamily of receptors. The protein may be involved in the regulation of antigen presentation. A soluble form of this protein can bind to dendritic cells and inhibit their maturation. Three transcript variants encoding different isoforms have been found for this gene. Recombinant human CD83 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.
7344 | CD83 human recombinant DataSheet
Biomolecule/Target: CD83
Synonyms: CD83 antigen isoform b precursor, BL11, HB15
Alternates names: CD83 antigen isoform b precursor, BL11, HB15
Taglines: Involved in the regulation of antigen presentation
NCBI Gene ID #: 959
NCBI Gene Symbol: CD40-L
Gene Source: Human
Accession #: P29965
Recombinant: Yes
Source: E. coli
Purity by SDS-PAGEs: 98%
Assay: SDS-PAGE
Purity: N/A
Assay #2: N/A
Endotoxin Level: N/A
Activity (Specifications/test method): N/A
Biological activity: N/A
Results: N/A
Binding Capacity: N/A
Unit Definition: N/A
Molecular Weight: 16 kDa (148 aa, 20-144 aa + His Tag), confirmed by MALDI-TOF.
Concentration: 0.25 mg/ml
Appearance: Liquid
Physical form description: 0.25 mg/ml in 20 mM Tris-HCl buffer (pH 8.0) containing 0.15 M NaCl and 30% glycerol.
Reconstitution Instructions: N/A
Amino acid sequence: MGSSHHHHHH SSGLVPRGSH MGSTPEVKVA CSEDVDLPCT APWDPQVPYT VSWVKLLEGG EERMETPQED HLRGQHYHQK GQNGSFDAPN ERPYSLKIRN TTSCNSGTYR CTLQDPDGQR NLSGKVILRV TGCPAQRKEE TFKKYRAE