Description
CDC23 Polyclonal Antibody | E-AB-15982 | Gentaur UK, US & Europe Distribution
Type: Polyclonal Antibody
Synonyms: ANAPC8, Anaphase promoting complex subunit 8, Anaphase-promoting complex subunit 8, Apc 8, APC8, Cdc 23, CDC23, CDC23, cell division cycle 23, Cell division cycle 23 homolog, Cell division cycle protein 23, Cell division cycle protein 23 homolog, Cut23, Cyclosome subunit 8
Application: IHC, ELISA
Reactivity: Human, Mouse
Host: Rabbit
Isotype: IgG
Reserch Areas: Cancer, Cell Biology
Background: The protein encoded by this gene shares strong similarity with Saccharomyces cerevisiae Cdc23, a protein essential for cell cycle progression through the G2/M transition. This protein is a component of anaphase-promoting complex (APC), which is composed of eight protein subunits and highly conserved in eukaryotic cells. APC catalyzes the formation of cyclin B-ubiquitin conjugate that is responsible for the ubiquitin-mediated proteolysis of B-type cyclins. This protein and 3 other members of the APC complex contain the TPR (tetratricopeptide repeat), a protein domain important for protein-protein interaction.
Concentration: 0.6 mg/mL
Storage: Store at -20°C. Avoid freeze / thaw cycles.
Immunogen: Synthetic peptide of human CDC23
Buffer: PBS with 0.05% sodium azide and 50% glycerol, PH7.4
Purification Method: Affinity purification
Dilution: IHC 1:50-1:200
Clone: N/A
Conjugation: Unconjugated
Molecular Weight(Calculated): N/A
Molecular Weight(Observed): N/A