BW
CDC42BPA polyclonal Antibody | BS60785
- SKU:
- BW-BS60785
- Availability:
- Usually ships in 5 working days
Description
CDC42BPA polyclonal Antibody | BS60785 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human,Mouse
Application: WB
Application Range: WB: 1:500~1:1000
Background: Protein kinases comprise a large group of encoded factors that regulate cellular processes by catalyzing the transfer of a phosphate group to a hydroxyl acceptor in serine, threonine or tyrosine residues . Myotonic dystrophy kinase-related Cdc42-binding (DMPK-like) kinases-a and b (MRCK-a, b) contain a cysteine-rich motif and a putative pleckstrin homology domain . MRCKs can phosphorylate nonmuscle myosin light chain and influences actin-myosin contractility . MRCK-a can phosphorylate and activate LIM kinases downstream of Cdc42, which leads to inactivation of ADF/cofilin and to Actin cytoskeletal reorganization . MRCK-a can also influence neurite outgrowth promoted by Cdc42 and Rac .
Storage & Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.
Specificity: CDC42BPA polyclonal Antibody detects endogenous levels of CDC42BPA protein.
Molecular Weight: ~ 186kDa
Note: For research use only, not for use in diagnostic procedure.
Alternative Names: Serine/threonine-protein kinase MRCK alpha; CDC42-binding protein kinase alpha; DMPK-like alpha; Myotonic dystrophy kinase-related CDC42-binding kinase alpha; MRCK alpha; Myotonic dystrophy protein kinase-like alpha; CDC42BPA; KIAA0451
Immunogen: A synthetic peptide corresponding to residues in Human CDC42BPA.
Conjugate: Unconjugated
Modification: Unmodification
Purification & Purity: The Antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen and the purity is > 95% (by SDS-PAGE) .
Pathway: