CDC42EP3 Antibody | 23-614

CDC42EP3 Antibody | 23-614 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human CDC42EP3 (NP_006440.2) .

Research Area: Cell Cycle, Immunology, Signal Transduction

Tested Application: WB

Application: WB: 1:500 - 1:2000

Specificiy: N/A

Positive Control 1: 293T

Positive Control 2: K-562

Positive Control 3: NIH/3T3

Positive Control 4: Rat heart

Positive Control 5: N/A

Positive Control 6: N/A

Molecular Weight: Observed: 37kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: BORG2, CEP3, UB1, cdc42 effector protein 3, CDC42 effector protein (Rho GTPase binding) 3, CRIB-containing BORG2 protein, MSE55-related Cdc42-binding protein, MSE55-related protein, binder of Rho GTPases 2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants.