Description
CDC42EP3 Antibody | 23-614 | Gentaur UK, US & Europe Distribution
Host: Rabbit
Reactivity: Human, Mouse, Rat
Homology: N/A
Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 1-254 of human CDC42EP3 (NP_006440.2) .
Research Area: Cell Cycle, Immunology, Signal Transduction
Tested Application: WB
Application: WB: 1:500 - 1:2000
Specificiy: N/A
Positive Control 1: 293T
Positive Control 2: K-562
Positive Control 3: NIH/3T3
Positive Control 4: Rat heart
Positive Control 5: N/A
Positive Control 6: N/A
Molecular Weight: Observed: 37kDa
Validation: N/A
Isoform: N/A
Purification: Affinity purification
Clonality: Polyclonal
Clone: N/A
Isotype: IgG
Conjugate: Unconjugated
Physical State: Liquid
Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Concentration: N/A
Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.
Alternate Name: BORG2, CEP3, UB1, cdc42 effector protein 3, CDC42 effector protein (Rho GTPase binding) 3, CRIB-containing BORG2 protein, MSE55-related Cdc42-binding protein, MSE55-related protein, binder of Rho GTPases 2
User Note: Optimal dilutions for each application to be determined by the researcher.
BACKGROUND: This gene encodes a member of a small family of guanosine triphosphate (GTP) metabolizing proteins that contain a CRIB (Cdc42, Rac interactive binding) domain. Members of this family of proteins act as effectors of CDC42 function. The encoded protein is involved in actin cytoskeleton re-organization during cell shape changes, including pseudopodia formation. A pseudogene of this gene is found on chromosome 19. Alternative splicing results in multiple transcript variants.