CDE-096 | B2663

CDE-096 is a high affinity, synthetic inactivator of plasminogen activator inhibitor-1 (PAI-1). CDE-096 binds to PAI-1 with nanomolar affinity and induces conformational changes that prevent binding to both proteases and vitronectin. This allosteric mechanism is characterized by reciprocal communication between the high-affinity compound-binding and vitronectin-binding sites.

CDE-096 is a high affinity, synthetic inactivator of plasminogen activator inhibitor-1 (PAI-1). CDE-096 binds to PAI-1 with nanomolar affinity and induces conformational changes that prevent binding to both proteases and vitronectin. This allosteric mechanism is characterized by reciprocal communication between the high-affinity compound-binding and vitronectin-binding sites.

B2663 | CDE-096 DataSheet

Alternate Name/Synonyms: CDE096; 3-(((3-(trifluoromethyl)phenoxy)carbonyl)amino)propane-1,2-diyl bis(3,4,5-trihydroxybenzoate)

Appearance: Crystalline solid

Formulation:

CAS Number: 1228357-04-7

Structure Available?: Yes

Peptide sequence: N/A

Salt Form: No

Molecular Formula: C₂₅H₂₀F₃NO₁₂

Molecular Weight: 583.42

Cell-Permeable?: True

Purity: ≥98% by HPLC

Solubilities: in DMSO

Handling: Do not take internally. Wear gloves and mask when handling the product! Avoid contact by all modes of exposure.

Country of Origin: USA

Tag Line: Novel inactivator of plasminogenactivator inhibitor-1

MDL Number:

PubChem CID: N/A

SMILES: O=C(NCC(OC(C1=CC(O)=C(O)C(O)=C1)=O)COC(C2=CC(O)=C(O)C(O)=C2)=O)OC3=CC=CC(C(F)(F)F)=C3

InChi: InChI=1S/C25H20F3NO12/c26-25(27,28)13-2-1-3-14(8-13)41-24(38)29-9-15(40-23(37)12-6-18(32)21(35)19(33)7-12)10-39-22(36)11-4-16(30)20(34)17(31)5-11/h1-8,15,30-35H,9-10H2,(H,29,38)

InChi Key: OXWKLJPAKUDPJY-UHFFFAOYSA-N