CDK1 Antibody [8C3G11] | 13-010

CDK1 Antibody [8C3G11] | 13-010 | Gentaur UK, US & Europe Distribution

Host: Mouse

Reactivity: Human, Mouse, Rat

Homology: N/A

Immunogen: Recombinant protein of human CDK1

Research Area: Apoptosis, Cell Cycle, Immunology, Neuroscience, Signal Transduction

Tested Application: WB, ICC

Application: WB: 1:100 - 1:200
ICC: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: Jurkat

Positive Control 2: A-549

Positive Control 3: K-562

Positive Control 4: HeLa

Positive Control 5: MCF7

Positive Control 6: A-431

Molecular Weight: Observed: 37kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Monoclonal

Clone: [8C3G11]

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CDC2, CDC28A, CDK1, DKFZp686L20222, MGC111195, CDC2, P34CDC2

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF) , which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.