CDK9 Antibody | 16-157

CDK9 Antibody | 16-157 | Gentaur UK, US & Europe Distribution

Host: Rabbit

Reactivity: Human, Mouse

Homology: N/A

Immunogen: Recombinant fusion protein containing a sequence corresponding to amino acids 153-372 of human CDK9 (NP_001252.1) .

Research Area: Cell Cycle, Immunology, Signal Transduction

Tested Application: WB, IHC, IF, IP

Application: WB: 1:1000 - 1:3000
IHC: 1:50 - 1:200
IF: 1:50 - 1:200
IP: 1:50 - 1:100

Specificiy: N/A

Positive Control 1: A549

Positive Control 2: HeLa

Positive Control 3: U-251MG

Positive Control 4: Raji

Positive Control 5: BT-474

Positive Control 6: Mouse spleen

Molecular Weight: Observed: 40kDa

Validation: N/A

Isoform: N/A

Purification: Affinity purification

Clonality: Polyclonal

Clone: N/A

Isotype: IgG

Conjugate: Unconjugated

Physical State: Liquid

Buffer: PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Concentration: N/A

Storage Condition: Store at -20˚C. Avoid freeze / thaw cycles.

Alternate Name: CDK9, RP11-228B15.5, C-2k, CDC2L4, PITALRE, TAK, CTK1

User Note: Optimal dilutions for each application to be determined by the researcher.

BACKGROUND: The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and known as important cell cycle regulators. This kinase was found to be a component of the multiprotein complex TAK/P-TEFb, which is an elongation factor for RNA polymerase II-directed transcription and functions by phosphorylating the C-terminal domain of the largest subunit of RNA polymerase II. This protein forms a complex with and is regulated by its regulatory subunit cyclin T or cyclin K. HIV-1 Tat protein was found to interact with this protein and cyclin T, which suggested a possible involvement of this protein in AIDS.