CDX1 Antibody (C-term) [AMM22151G]

CDX1 Antibody (C-term) [AMM22151G] | Gentaur UK, US & Europe Distribution

Product Category: Monoclonal Antibodies

Host: Mouse

Species Reactivity: H, M

Specificity: Purified His-tagged CDX1 protein was used to produced this monoclonal antibody.

Cellular Localisation: Nucleus.

Molecular Weight: 28138

Clone: Monoclonal

Gene Name: CDX1

Gene ID: 1044

Function: Plays a role in transcriptional regulation (PubMed:24623306) . Involved in activated KRAS-mediated transcriptional activation of PRKD1 in colorectal cancer (CRC) cells (PubMed:24623306) . Binds to the PRKD1 promoter in colorectal cancer (CRC) cells (PubMed:24623306) . Could play a role in the terminal differentiation of the intestine. Binds preferentially to methylated DNA (PubMed:28473536) .

Summary: Tissue Location: Intestinal epithelium.

Form: Purified monoclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.

Storage: Store at +4°C short term. For long-term storage, aliquot and store at -20°C or below. Stable for 12 months at -20°C. Avoid repeated freeze-thaw cycles.

Application: WB

Dilution: WB--1:1000-1:2000

Synonyms: Homeobox protein CDX-1, Caudal-type homeobox protein 1, CDX1